- Stan Lee (12 movies)
- Sean Connery (9 movies)
- Samuel L. Jackson (8 movies)
- Sigourney Weaver (8 movies)
- Sean Bean (7 movies)
- Stellan Skarsgård (7 movies)
- Scarlett Johansson (5 movies)
- Shia LaBeouf (5 movies)
- Simon Pegg (5 movies)
- Sung Kang (5 movies)
- Samantha Bond (4 movies)
- Sean Astin (4 movies)
- Seth Green (4 movies)
- Shawn Ashmore (4 movies)
- Shefali Chowdhury (4 movies)
- Sofia Coppola (4 movies)
- Spencer Wilding (4 movies)
- Stephen Fry (4 movies)
- Steve Coogan (4 movies)
- Sylvester Stallone (4 movies)
- Sala Baker (3 movies)
- Sally Field (3 movies)
- Sam Neill (3 movies)
- Sam Rockwell (3 movies)
- Sam Spruell (3 movies)
- Sammy Davis (3 movies)
- Sarah Gadon (3 movies)
- Sasha Barrese (3 movies)
- Scarlett Byrne (3 movies)
- Scott Eastwood (3 movies)
- Scott Glenn (3 movies)
- Sean Biggerstaff (3 movies)
- Sean Penn (3 movies)
- Seann William Scott (3 movies)
- Sergio Kato (3 movies)
- Shad Moss (3 movies)
- Shane Rimmer (3 movies)
- Shannon Elizabeth (3 movies)
- Sharon Tay (3 movies)
- Shea Whigham (3 movies)
- Sherry Lynn (3 movies)
- Shirley Henderson (3 movies)
- Shirley MacLaine (3 movies)
- Silas Carson (3 movies)
- Simon McBurney (3 movies)
- Sofia Helin (3 movies)
- Sondra Currie (3 movies)
- Stanley Tucci (3 movies)
- Stephen Graham (3 movies)
- Stephen Hunter (3 movies)